The prognosis of the patient was good without AEH recurrence or cancer, suggesting that the size of the lump is not critical in determining a therapeutic plan. In the current case, the patient accepted the traditional therapy without surgery even though a large mass was found. To determine the therapeutic plan, physicians must balance the risk of cancer with the desire of the patient to become pregnant. The intrauterine lump is commonly removed by surgery to decrease the risk of cancer, although the patient will no longer be able to become pregnant. Endometrial hyperplasia was identified as a precancerous pathological change. This is an interesting case because the patient was at a reproductive age, and AEH is uncommon in this age group. If B-scan ultrasound and magnetic resonance imaging (MRI) results suggest that the intrauterine masses may be malignant, a pathological report should be obtained to provide a basis for the next steps. The aim of this study was to describe a rare case, in order to aid gynecologists in determining the appropriate management of abnormal uterine bleeding and intrauterine masses. This case study will be beneficial for gynecologists for the diagnosis and treatment of patients with AEH. Here, we report a rare case of AEH in a 35-year-old patient, who was diagnosed according to the 2014 World Health Organization classification of tumors of female reproductive organs. With increasing AEH diagnoses, AEH and EC patients are being diagnosed at younger ages, and up to 22%-66% of AEH patients are infertile. It is estimated that 47130 new EC cases and 8010 EC deaths occurred in the United States in 2012.Īlthough 20%-25% of EC patients are diagnosed before menopause, 2%-14% of EC patients are younger women (< 40-years-old) thus, preservation of their fertility is required when a therapeutic plan is determined. Endometrial cancer (EC) is the most common tumor of the female genital tract in developed countries, ranking fourth in incidence among invasive tumors in women. Although 29% of cases can develop into endometrial carcinoma within 5 years if not treated in time due to the continuous effect of estrogen, the frequency and significance remain a subject of debate. Atypical endometrial hyperplasia (AEH) is a common disorder in women, which leads to cancer in about 25% of cases.
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